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You can help yourself by asking the doctor to check vitamin B12 if youve noticed any related symptoms, or by asking for a proactive check if you have any risk factors

Acknowledgments Authors want to thank Germaine Pugh and Cassia McClain for their invaluable help in preparing the manuscript, and Jessica Michelle Vasquez-Soltero for processing the gene profiling data

Problems with intrinsic factor binding to ileal receptors in the diseased tissue leads to B12 deficiency

TGF-1/Smad Pathway Inhibition in Hepatic Stellate Cells TGF-1 drives HSC fibrogenic activation through canonical Smad2/3 phosphorylation (ALK4/5Smad2-Ser423/425

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