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What Is Semaglutide and How Does It Affect Patients

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The trial involved 1879 patients with inadequate glycemic control on metformin monotherapy, who were randomly assigned to receive tirzepatide at doses of 5 mg, 10 mg, or 15 mg, or semaglutide at a dose of 1 mg.After 40 weeks of treatment, all doses of tirzepatide were found to be noninferior and superior to semaglutide in terms of reducing glycated hemoglobin (HbA1c) levels

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As it is part of the G protein-coupled receptor family, it has a wide distribution through the body, predominantly localizing to the cellular membrane (138)