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The median change from baseline in daily dose of insulin was zero for both groups at the end of the study

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In patients who develop unexplained lethargy, vomiting, or changes in mental status, hyperammonemic encephalopathy should be considered and an ammonia level should be measured [seeContraindications (4)andWarnings and Precautions (5.6, 5.9)]

Enzymatic reactions were performed using phosphate buffer of different pH values