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Gu YJ, Cheng J, Man CW, Wong WT, Cheng SH

It may also reduce sugar absorption in the intestines and promote balanced blood sugar, making it a powerful asset for weight control

IAPAMs May 2026 clinical guidance on GLP-1 management lays out what that management actually involves: dose titration over months to find the effective level, metabolic monitoring at appropriate intervals A1C, lipid panels, blood pressure active management of side effects including nausea and GI symptoms, screening for contraindications including thyroid history and pancreatitis risk, and integration with nutritional and behavioral support

Subgroup analysis revealed that oral semaglutide significantly reduced the risk of AF (RR 0.49, 95% CI 0.25 to 0.97), whereas subcutaneous semaglutide did not have a significant effect (RR 0.80, 95% CI 0.57 to 1.12)