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10.1002/acn3.125 73 StinoA

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Berberine may interact with several medicines through effects on liver enzymes (CYP3A4) and transport proteins (P-glycoprotein), potentially affecting levels of medicines such as ciclosporin, tacrolimus, digoxin and some anticoagulants

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According to USDA Agricultural Research Service data based on NHANES, approximately 6% of adults aged 60 and older in the United States are vitamin B12 deficient, defined as plasma B12 below 148 pmol/L (2009)

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