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KPV, a short fragment of alpha-MSH, is known for its anti-inflammatory and antimicrobial effects, mainly by reducing overactive immune signaling

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Crucially, the researchers explored substituting these expensive growth factors with a small-molecule cocktail, specifically 10 g/mL Vitamin C, 0.1 M Dihexa, and 10 M Forskolin (VDF cocktail), to assess its efficacy in inducing hepatic specification