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Hypoxia or genetic alterations leading to stabilization of HIF induce tumor angiogenesis Hyper-proliferation of tumor cells results in increased oxygen consumption, and when the tumor mass surpass the blood supply the tumor becomes hypoxic

Research protocols in animals have used doses ranging from 1 mcg/kg/day to 120 mcg/kg/day depending on the model and endpoint

These conditions affect up to 15 % of pregnancies and are recognised as one of the leading causes of maternal and fetal death globally (Reference Kassebaum, Barber and Bhutta99)

Hair growth cycles require 3-6 months to show visible improvements from nutritional changes

Each person is different and each person has different needs, the effects will be related to those factors