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Author contributions D-LQ, C-PC, and Y-HB conceived and designed the experiments

Table 12: Study of Different Times of Once Daily Insulin Glargine Dosing in Type 1 (Study H) and Type 2 (Study I) Diabetes Mellitus Progression of Retinopathy Evaluation in adults with Diabetes Type 1 and Diabetes Type 2 Insulin glargine was compared to NPH insulin in a 5-year randomized clinical study that evaluated the progression of retinopathy as assessed with fundus photography using a grading protocol derived from the Early Treatment Diabetic Retinopathy Scale (ETDRS)

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however, the combination had the strongest effects

First, it includes a large, unselected cohort representative of routine clinical practice