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The following groups of subjects were excluded: pregnant women, individuals with excessive alcohol intake, chronic smokers and those receiving antioxidants, those with clinical infection and an inflammatory or malignant disease

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Nevertheless, we can mainly divide them into the extrinsic and intrinsic apoptosis signalling pathways regulated by activated caspases and molecular systems such as Bcl-2/Bax and Fas/Fas ligand [39, 40]