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It is clear from this study that chronic l-carnitine supplementation stimulates TMAO concentrations in humans Research has shown that red meat has raised the risk of heart disease and colon cancer

at high doses , it can become neurotoxic or act as a pro-oxidant

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Hyperseborrhea can result from hormonal factors, notably an increased sensitivity of the sebaceous glands to androgens, as well as from genetic predispositions, disturbances in the skin microbiota, or environmental factors

doi:10.2165/00003088-200342110-00002