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28 Mercury, cadmium, and lead, for example, can effectively inhibit cellular glutathione peroxidase, reducing the effectiveness of this antioxidant defense system for detoxification

However, other findings indicate that microglial activation, enhanced neuroinflammation, and oxidative damage occur before brain atrophy after chronic alcohol ingestion [9,10]

These aren't necessarily absolute GHK-Cu contraindications for every single case, but they represent situations where the risk-benefit analysis becomes much more complicated

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