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Compared with the WT group, the control group spent significantly less time ( P = 0.0076
Because of the importance of these functions, the enzymes involved in NAD metabolism are targets for drug discovery
doi: 10.1016/j.ejphar.2015.12.019 130 ChenJWangWJiangMYangMWeiW
These include inhibition strategies of NAD + consuming enzymes, such as CD38 and PARPs, or modulation of key NAD + synthesis proteins such as NAPRT and NAMPT, as summarized below and in Fig
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