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Beside its fundamental function in SA biosynthesis, GNE was suggested to regulate sialyltransferase mRNA levels, affecting cell proliferation 8

doi: 10.3389/fbioe.2021.677576

Moreover, GCs induce a post-receptor defect by decreasing key mediators of insulin action in peripheral tissues (insulin receptor substrate-1, PI3K, and protein kinase B) [82]

doi:10.2174/1381612043384655

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