The SELECT cardiovascular outcomes trial (NEJM, 2023) showed a 20% reduction in major adverse cardiovascular events among patients with existing heart disease -- data that no other GLP-1 in this class has yet matched
As anticipated, the ability of the KASH-fusions of zDHHC3, 7, and 11 to induce ONM accumulation of Go-Nt 7 and MGNC-Nt 7 was completely abolished when DHHS-mutants were co-expressed (Fig
Sustainable weight loss is about metabolic health, not just the number on the scale
Los pacientes deben discutir su historial cardiovascular completo con su proveedor de salud, incluyendo cualquier antecedente de insuficiencia cardaca, arritmias o eventos cardiovasculares previos
Age, injury, disease all of these reduce copper availability, and the enzymes downstream suffer for it