Here are some symptoms of undermethylation to look out for: [22] Elevated homocysteine levels Depression Irritability Anxiety Multiple miscarriages Multiple chemical sensitivities Sensitivity to anesthetics Red face that lasts after exercising Allergies Being prone to addiction High libido Obsessive-compulsive disorder (OCD) Low pain threshold Headaches/migraines Digestive problems (such as IBS) Brain fog (especially after protein-rich meals) Insomnia High estrogen levels/estrogen dominance Low energy/fatigue Muscle pain Low levels of neurotransmitters (dopamine, norepinephrine, and serotonin) Heavy menstrual periods with blood clots Flakey skin rash under your nose* Lowered immunity* *Although I havent seen this in the research, its been an observation for me personally, as well as for a few clients, that difficulty fighting off viral infections as well as having a red rash under the nose, seems to correlate with poor methylation
it is a condition defined by ongoing communication between the stomach, immune system, and CNS
This combination makes it relevant not just for aesthetic outcomes but for the broader inflammatory burden that accelerates aging in metabolically active tissues
Additionally, its ability to optimize energy utilization may help maintain lean muscle mass during weight loss
In this parallel clinical study, ivermectin was administered as nasal spray (1 ml in each nostril two times daily) and compared with oral ivermectin against standard care (which was oxygen via mask or ventilator)
