Women of childbearing potential should use effective contraception, and some agents (notably semaglutide) require a washout period of at least 2 months before planned conception
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Day 0 (the day prednisone is prescribed): Continue Zepbound on the regular weekly schedule Get a baseline finger-stick glucose if you have a meter, or note your continuous glucose monitor (CGM) reading Plan to monitor glucose 2 to 4 times daily during the steroid course Have a Tums or Pepcid plan in case reflux flares Days 1-5 (the steroid course): Take prednisone in the morning with food, as prescribed Continue Zepbound on schedule Check fasting glucose first thing in the morning Check post-meal glucose 2 hours after lunch and dinner Hydrate well (steroids increase thirst
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