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Our results showed that RA patients have a higher risk of getting CTS regardless of whether the ebi database (IVW, OR = 1.045, 95% CI: 1.0161.075, P = 0.002) or the GEO database (IVW, OR = 1.001, 95% CI: 1.0011.002, P = 0.001) is selected for CTS data

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Finally, ubiquitin ligase E3 identifies specific target proteins and transfers ubiquitin from E2 to the lysine residue on the target protein

Microbial metabolites such as short-chain fatty acids (SCFAs) and tryptophan-derived ligands further modulate intestinal barrier integrity, immune tone, and nutrient absorption efficiency [70]