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New Engl J Med (2018) 378(14):130212

Key characteristics: Structure: Five amino acids (Aib-His-D-2-Nal-D-Phe-Lys-NH2) Classification: Third-generation GHRP Mechanism: Growth hormone secretagogue receptor (GHS-R) agonist Half-life: Approximately 2 hours Administration: Subcutaneous injection Ipamorelin was initially developed to accelerate gastrointestinal recovery after bowel surgery

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The variance components were used to simulate 1000 data sets, with the 25 % effect size in the senior group