tirzepatide and heart issues UC Irvine researchers project cardiac benefits from weight-loss medication Bridging the gap between GLP1-receptor

This review summarizes that the effect of GLP-1 is not just through its peripheric effects, but also through its central effects on reward processing as assessed by injection of GLP-1 analogs or GLP-1 itself to intra-NTS, NAc, VTA, LH, lPBN, SUM, BNST, LS for palatable food intake, intra-VTA, NAc, and LS for cocaine, intra-NAc for amphetamine, intra-NAc, NTS, dLS for alcohol, and intra-NTS and IPN for cocaine

Other adverse effects include: Constipation especially with verapamil

However, drugs that provide long-term effects of treatment and/or target later phase after stroke might be more crucial, because a prolonged time-window of treatment applies to most of new victims, as well as dysfunction is persistent in patients with stroke (7, 155)

10.3410/f.1119928.576041 27 KnopikV

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