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Glutathione is a required substrate for a family of enzymes called glutathione S-transferases, which conjugate glutathione to reactive compounds including drug metabolites and environmental toxins making them water-soluble for excretion

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In db/db mice, the administration of BHB was shown to increase the levels of autophagy markers, including LC3 (Map1lc3a), p62 (Sqstm1), and beclin (Atg6), as well as enhance autophagic flux in the kidneys [9]

The importance of healthy vagus nerve function in healing leaky gut syndrome can therefore not be overstated

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