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Peer review Peer review information Nature Communications thanks Chengyong Tang and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

When to Start Another TB-500 Cycle The decision to begin a new cycle should be based on clinical need, not just a calendar schedule

IGF-1R deficiency in human keratinocytes disrupts epidermal homeostasis and stem cell maintenance

A steady routine aligned with the skin cycle works better than using aggressive peels occasionally

A separate experiment was conducted to confirm the effect of Bd infection using (mBCI) a glutathione fluorescent probe which emits blue fluorescence when conjugated with glutathione (30)