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The rates of major birth defects, excluding genetic or chromosomal anomalies and those associated with intrauterine infections, were similar in both the GLP1-RA exposed group and the reference group with diabetes (2.6% and 2.3%, respectively)

Additional data have shown a correlation between diminished CD4+ T cell counts and increased levels of pro-inflammatory cytokines (IL-1, IL-17, and IL-6) that contribute to systemic inflammation, and malondialdehyde (MDA), which is an end-product of lipid-peroxidation and a marker for oxidative stress

However, factors such as aging, stress, and environmental toxins can deplete glutathione levels, necessitating the need for dietary and supplemental interventions to support its production