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4, explained that he first began seriously considering losing weight on his 39th birthday because "I knew my next one was 40 I don't think I've ever met a 500-pound 40-year-old." He said that he'd felt like he'd "already cheated the game" after dealing with "multiple heart issues." "I was like, Man, I should really start trying to figure this out I could feel myself dying, Joe," he said

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One of the concerns with any rapid weight loss, whether from GLP-1 medications, calorie restriction, or surgery, is the loss of lean body mass alongside fat

In the spring of 1983 Mojsov took up a position in Boston as an instructor in medicine and assistant in biochemistry in the Endocrine Unit of MGH

Isoleucine (Ile, I) MW: 131.17 Da Residue mass: 113.08 Da Nonpolar, aliphatic, branched-chain