August 28, 2025
In the early adhesion phase, immune defenses are active: neutrophils and M1 macrophages target bacteria via phagocytosis, oxidative bursts, increased antimicrobial peptides (AMPs), reactive oxygen species (ROS), and pro-inflammatory cytokines (IL-1, IL-6, TNF-) and chemokines
doi:10.1016/j.mce.2015.04.008
Additional functions include 9,10 : Balancing blood pH Facilitating the conversion of vitamin D into its active form (ie, 1,25-dihydroxycholicalciferol) Producing hormones that help control blood pressure and red blood cell production Maintaining normal blood concentrations of electrolytes (eg, potassium, sodium, phosphorus, and calcium) Kidney damage and the loss of function may gradually lead to CKD
If you experience consistent histamine reactions with redness and itching, consider taking a natural antihistamine like quercetin before your injection