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Moreover, GLP-1R antagonism partly reduced plasma TGs and this effect could be explained by the GLP-1R-mediated insulin secretagogue effect of G49 that likely accounts for insulin-mediated de novo lipogenesis rather than a direct effect of G49 actions in the liver through the GLP-1R which is nearly absent as reported 54

This question concerns many patients considering or currently taking this dual GIP/GLP-1 receptor agonist for type 2 diabetes or weight management

Anti-inflammatory, Antioxidant, and Anti-apoptotic Effects of Carnitine