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If you take levothyroxine and Rybelsus, this is especially important to mention due to potential increased levothyroxine exposure

Adjusting for Individual Needs : You may need more water if you are physically active, live in a hot climate, or are pregnant or breastfeeding

However, individuals with very low body fat may benefit from gently pinching the skin to create a fold of subcutaneous tissue, ensuring the needle reaches fatty tissue rather than muscle