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Patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 should not use GLP-1 medications due to a theoretical risk of thyroid tumors observed in animal studies

Participants exhibiting acute signs of illness within 2 weeks of enrollment such as vomiting, diarrhea, fever, cough, or ear infection were rescheduled

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PMID 40353578