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We used Bonferroni correction on the p -values of the piecewise regression to account for multiple comparisons ( N = 5 instruments 2 sexes M metabolites), and deemed adjusted p -values below 0.05 to be statistically significant

doi: 10.1111/j.1365-2125.1995.tb05779.x

Standard practice is brief draw-and-return handling rather than extended counter time

Tirzepatide (GLP-1/GIP agonist): In pharmacovigilance analyses, semaglutide showed a stronger signal for depression reports, whereas tirzepatide did not despite tirzepatides potent metabolic effects (eClinicalMedicine 2025)

Quality assurance teams appreciate the consistent performance characteristics of properly encapsulated products