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Expanding mutational and clinical spectra of the PTEN hamartoma tumour syndrome

And, when the V max values are set to 10% of their normal values, the number of functional hepatocytes decreases to 10% of normal after 40 hours (the red curve), well below the grey bar marking 30% remaining hepatocytes, which is thought to be the threshold for liver failure[10]

Both conditions involve symptoms of gastrointestinal bleeding, though a major difference is that hematochezia often presents as bright red blood in the stool, while melena appears as black, tarry stool

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The Mutational Landscape of Mucosal Melanoma