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Furthermore, the amide group can also be transferred to formylglycinamide ribonucleotide (FGAR), which in turn forms formylglycinamidine ribonucleotide (FGAM) for nucleotide synthesis by phosphoribosylformylglycinamidine synthase (PFAS)

M., Parreiras-E-Silva, L

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J.YeckelC

FLNA is composed of two subunits of 280 kDa each that self-assemble, each monomer possesses an actin-binding domain (ABD) at the N-terminus, that consists of two calponin homology domains, followed by 24 immunoglobulin (Ig)-like repeats of about 96 amino acid residues