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Gastrointestinal issues: Nausea, abdominal cramps, and diarrhea can occur

Ongoing studies continue to expand our understanding of its role in antioxidant defense, mitochondrial physiology, detoxification pathways, immune regulation, and cellular resilience under conditions of physiological stress

(2013, October 28)

GSH can modulate the activity of various redox-sensitive signaling pathways, including the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, which regulates the expression of antioxidant and detoxification genes, and the mitogen-activated protein kinase (MAPK) pathway, which regulates cell proliferation, differentiation, and apoptosis

The identification of ferroptosis in disease models is increasingly recognized as a key research direction for elucidating disease mechanisms and developing novel therapeutic strategies