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The literature is controversial regarding which ligaments are tightest in varying positions of forearm supination or pronation, but acute or delayed complaint of ulnar-sided wrist pain, often radiating dorsally and exacerbated by firm grasp and push-off (wrist extended, getting up from a table) is a characteristic features of the patients history

Moreover, mechanistic interpretations derived from spectroscopic studies of interactions with biomolecules such as DNA or HSA remain largely indirect and require further biochemical validation