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Nat Cell Biol 22(4):476486

Dihexa is a peptide variant derived from angiotensin IV which has been found to potently improve cognitive function in animal models of diseases such as Alzheimer's

Notably, under hypoxic or electron transportlimited conditions, SDH can reverse its activity to reduce fumarate to succinate using electrons from the CoQ 10 pool, a metabolic rerouting, allowing cells to maintain redox balance when oxygen is scarce 77

A diagnosis of gastroparesis, stomach paralysis, ileus, gastric intestinal obstruction, or a related condition while taking these medications or within 30 days of using them (our lawyers are also investigating pulmonary embolism and aspiration eligibility)

Be cautious with the use of corticosteroids (e.g., prednisone) and monitor blood glucose levels closely