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These findings indicate that TTP, in particular, may serve as a potential antihypertensive candidate with potent ACE-inhibitory activity [177]

For an 80 kg test subject, this would give a weekly dosage range of between 2,400-4,800 g (2.4 4.8 mg)

Follow the 5 on, 2 off dosing schedule

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Safety Considerations and Who Should Start Conservatively Female patients with liver disease, severe kidney impairment, or uncontrolled thyroid dysfunction require careful dosing oversight and may need lower starting doses or extended monitoring intervals