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DOI: 10.2147/DMSO.S494919, Rigamonti, A

The Company is developing nimacimab as a potential orthogonal add-on therapy for patients with obesity who are experienced on or have plateaued with GLP-1-based treatment, targeting clinically meaningful incremental weight loss, improved body composition, and reduced weight regain without added gastrointestinal or neuropsychiatric burden

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PSM achieved a good balance across measured covariates, and the inclusion of positive and negative control outcomes further supports internal validity

Inflammation in the brain has been linked to mood disorders like depression and anxiety, and some researchers think it might also play a role in conditions like OCD