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doi: 10.1210/jc.2008-2760 225 SiemensmaEPCde Lind van WijngaardenRFAOttenBJde JongFHHokken-KoelegaACS

MASH can lead to scarring of the liver and cirrhosis, and it is one of the most common reasons for liver transplants

In this review, we provide a description of recent advances of GLP-1-induced inhibition of feeding behaviors and modulation of neuronal electrophysiological activities in multiple brain nuclei located within the medulla oblongata, pons, mesencephalon, diencephalon, and telencephalon (Table 1)

Many people will also experience cognitive difficulties such as problems with vision, memory, thinking, or reasoning, the development of mental illnesses such as depression, or general changes in behavior

Unlike semaglutide, which activates only the GLP-1 receptor, or tirzepatide, which targets both GLP-1 and GIP, retatrutide engages three key metabolic receptors simultaneously: GLP-1 receptor curbs appetite, slows gastric emptying, and lowers blood sugar