In addition, it has been shown that SAG pretreatment significantly prevents CCl4-induced cytotoxicity, is protective in restoring mitochondrial autophagy, and attenuates fibrosis, collagen deposition, hepatocellular damage and organ dysfunction
Figure 2 Figure 3 Metabolites, such as phenolics, flavonoids, and tocopherols, can effectively mitigate oxidative stress and lower the risk of chronic diseases (Torres-Tiji et al., 2020)
Its ability to scavenge reactive oxygen species (ROS) is especially critical given the CNSs high metabolic activity and inherent susceptibility to oxidative stress-induced cellular injury
Cell Physiol Biochem 43:18801892 Leite NC, Viegas BB, Villela-Nogueira CA, Carlos FO, Cardoso CR, Salles GF (2019) Efficacy of diacerein in reducing liver steatosis and fibrosis in patients with type 2 diabetes and non-alcoholic fatty liver disease: a randomized, placebo-controlled trial
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