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Eye care specialists may need to evaluate and monitor patients with existing retinopathy more frequently during the initial months of treatment

The lesions are usually solitary and well circumscribed though a few authors have reported bilateral or multiple (Table 1) melanoacanthomas

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Some patients benefit from taking their weekly injection on a day when they can rest if mild discomfort develops, or timing injections to coincide with lighter work schedules during adaptation weeks

Le strategie terapeutiche attuali mirano ad ottimizzare il controllo glicemico attraverso varie modalit: a) incrementando la disponibilit di insulina circolante, mediante la somministrazione di insulina esogena oppure mediante farmaci che promuovono la secrezione di insulina endogena