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Given the crucial functions of vitamin B12 in our bodies, a deficiency can have negative effects on your health

If you are uncertain about timing with specific medications, consult your GP or pharmacist for personalised advice

Building on our previous work demonstrating the potential of nucleotide-based inhibitors with an acrylamide warhead to target KRAS G13C , we designed and synthesized a library of nucleotide-based compounds with cyclic linkers to explore the effect of warhead orientation on reactivity toward Cys13

Plasma glucose concentrations were unchanged during the test period and did not differ between the treatment groups

Tian et al., 2023