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Most users find 250-500 mcg daily balances effectiveness with tolerability

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The relationship appears to be with the rate and magnitude of weight loss itself rather than a direct drug effect

I would have drunk urine or vomit at that moment, my mouth contorting for one more drop of life, death inching and edging its way on me, shriveling in every pore and sucking my soul out, my raspy throat stinging like bees maddened by a poker, my tongue swelling, my lungs suffocating