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Copper-Specific Safety: Understanding Free Copper Total serum copper alone does not tell the full story

Nguyen TT, Ngo LQ , Promsudthi A, Surarit R

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Notably, choline transporter-like proteins (CTLs), especially CTL1 (SLC44A1) and CTL5 (SLC44A5), mediate high-affinity choline uptake in oligodendrocytes, a process essential for the biosynthesis of choline-derived plasmalogens (Traiffort et al., 2013)

The findings may have clinical implicationsespecially since the team also found that breast cancer samples from patients whose disease had spread to the lung showed elevated SLC25A39, and that higher SLC25A39 expression was strongly correlated with poorer overall survival in breast cancer patients