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In H 2 O 2 -induced oxidative stress models, curcumin has been shown to promote autophagy, potentially via inhibition of the AMPK/mTOR pathway in granulosa cells (Duan et al., 2024)

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A well-known risk factor in humans is hypercholesterolemia, i.e., elevated total cholesterol (TC) and low-density lipoprotein cholesterol (LDL) (Pourrajab et al., 2021), and other important contributors to this disease include inflammation, oxidative stress and insulin resistance (Subramani et al., 2017)