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Perez-Meza, D., et al

Many patients rotate between left and right sides of the abdomen on alternating days

More recently it has been demonstrated that these changes mediate a beneficial effect in models of T2D diabetes

If a small study bias was identified, we then performed the trim and fill computation to explore the effect of missing studies on the outcomes

In addition, information on disease severity, extent of skin involvement, and treatment response was unavailable, precluding analyses of doseresponse relationships or severity-specific outcomes