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An exploratory DEXA analysis of the STEP 1 semaglutide trial found a 9.7% reduction in total lean body mass over 68 weeks, alongside a 19.3% reduction in fat mass with fat lost at roughly twice the rate of lean tissue

Slowing progression if caught early combined with excellent glucose control

Consistent with these findings, experimental models demonstrate that T3 supplementation alleviates liver fibrosis by restoring mitochondrial biogenesis, enhancing -oxidation of fatty acids, and normalizing autophagic flux