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Probing the presumed catalytic triad of selenium-containing peroxidases by mutational analysis of phospholipid hydroperoxide glutathione peroxidase (PHGPx)

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Lifelong choline supplementation in another Alzheimers disease mouse model (APP/PS1 transgenic mice), significantly diminished amyloid- plaque load and decreased activated microglia, thereby mitigating the detrimental effects of brain inflammation associated with Alzheimers disease (165)

In the current study, neither TMA nor TMAO was found at elevated levels in either the HFD or HFD + L-carnitine group

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