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Here is what they contain, side by side with the doses that clinical studies actually used: The dosing gap is the core problem

Research suggests that addressing nutritional factors may help optimize body composition outcomes during GLP-1 treatment

Footnotes This work was supported by the US Department of Veterans Affairs (Veterans Health Administration, Office of Research and Development and Biomedical Laboratory Research and Development) and the National Institutes of Health (R01AR071653)

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The limitation is that GLP-1 drugs as approved by FDA are intended to treat obesity and diabetes, Lewis said