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Results of experimental studies

Lipid peroxidation and iron metabolism signals were considered as the key mediators of ferroptosis

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The importance of cysteine as a protein component is to give the active protein a free SH group, for example, the active centers of some proteases (papain, bromelain) and glyceraldehyde phosphate dehydrogenase all regard SH group as their function base

Sceniak MP, Spitsbergen JB, Sabo SL, Yuan Y, Atchison WD (2020) Acute neurotoxicant exposure induces hyperexcitability in mouse lumbar spinal motor neurons