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Uric acid protects neurons against excitotoxic and metabolic insults in cell culture, and against focal ischemic brain injury in vivo

Hepatotoxicity Warn patients and guardians that nausea, vomiting, abdominal pain, anorexia, diarrhea, asthenia, and/or jaundice can be symptoms of hepatotoxicity and, therefore, require further medical evaluation promptly [seeWarnings and Precautions (5.1)]

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Asthma may also coexist with obstructive sleep apnea (OSA), which has been termed alternative overlap syndrome [47] and has been considered by some as a possible separate phenotype [48]