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In a rat model of pulmonary arterial hypertension (PAH) induced by a single dose of monocrotaline, OXR1 and P21 gene expression and antioxidant capacity in lung tissue significantly decreased
High-profile examples of toxicities, such as those associated with acetaminophen, bromobenzene, and urushiol, reinforced the perception that electrophiles were no-go zones for drug development
For most researchers focused on weight management, the priority order is: adherence first, side effect management second, appetite alignment third
Caspases and their substrates
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