( Studies in Subjects With Mild Cognitive Impairment In a randomized, double-blind, placebo-controlled crossover study, 6 months followed by another 6 months of open-label extension of MCT (C8) supplementation with up to 42 g a day (25.2 g on average), given with meals, improved some cognitive assessment scores in elderly subjects with mild to moderate dementia ( Studies in Alzheimer's Disease Patients A PET study in Alzheimer's Disease (AD) patients demonstrated that 1 month of daily consumption of 30 g of MCT (C8+C10 or C8) led to mild ketonemia and increased total brain energy metabolism due to an increase in ketone body utilization ( Several studies of MCT supplementation in AD patients showed that the intervention efficacy depended on APOE4 status
Funding This research did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors
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